Neuropeptide Y / NPY Human, Rat Protein

CAT#: AR31131PU-L

Neuropeptide Y / NPY human, rat protein, 1.0 mg


USD 540.00

5 Days*

Size
    • 1 mg

Product Images

Specifications

Product Data
Species Human, Rat
Expression cDNA Clone or AA Sequence
YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY-CONH2 (1-Letter code).
H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2 (3-Letter code).
Predicted MW 4271.66 Da
Purity >95% by HPLC
Buffer State: Purified peptide
Preparation Purified peptide
Protein Description Neuropeptide Y (Human, Rat).
Formula: C189H285N55O57S
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: One year from despatch.
Reference Data
RefSeq NP_000896
Locus ID 4852
UniProt ID P01303, A4D158
Cytogenetics 7p15.3
Synonyms PYY4
Summary 'This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]'
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Adipocytokine signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.