Properdistatin Human Protein

CAT#: AR31132PU-L

Properdistatin protein, 5.0 mg

Specifications

Product Data

• Species: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  GPWEPCSVTCSKGTRTRRR-OH (1-Letter code).
• Predicted MW: 2177.47 Da
• Purity: >95% by HPLC
• Buffer: State: Purified peptide
• Preparation: Purified peptide
• Protein Description: Properdistatin peptide
  Formula: C₈₉H₁₄₇N₃₃O₂₇S
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.

Reference Data

• RefSeq: NP_001138724
• Locus ID: 5199
• Cytogenetics: Xp11.23
• Synonyms: BFD; PFC; PFD; PROPERDIN
• Summary: 'This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009]'
• Protein Families: Secreted Protein