SPG3A (ATL1) (NM_015915) Human Recombinant Protein
CAT#: TP302310
Purified recombinant protein of Homo sapiens atlastin GTPase 1 (ATL1), transcript variant 1
View other "ATL1" proteins (5)
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
>RC202310 representing NM_015915
Red=Cloning site Green=Tags(s) MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDEHSFELDETALNRILLSEAVRDKEVVAV SVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKV AVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLCTEYGRLAMEETFLKPFQ SLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNP NFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQA TAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQ LESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCT WAYIRYSGEYRELGAVIDQVAAALWDQGSTNEALYKLYSAAATHRHLYHQAFPTPKSESTEQSEKKKM TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Predicted MW | 63.4 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Note | For culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_056999 |
Locus ID | 51062 |
UniProt ID | Q8WXF7, A0A0S2Z5B0, Q53F53 |
Cytogenetics | 14q22.1 |
Refseq Size | 2271 |
Refseq ORF | 1674 |
Synonyms | AD-FSP; atlastin1; FSP1; GBP3; HSN1D; SPG3; SPG3A |
Summary | The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Transmembrane |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC405711 | ATL1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LC414318 | ATL1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY405711 | Transient overexpression lysate of atlastin GTPase 1 (ATL1), transcript variant 2 |
USD 605.00 |
|
LY414318 | Transient overexpression lysate of atlastin GTPase 1 (ATL1), transcript variant 1 |
USD 396.00 |
|
PH302310 | ATL1 MS Standard C13 and N15-labeled recombinant protein (NP_056999) |
USD 2,055.00 |
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