SPG3A (ATL1) Rabbit Polyclonal Antibody

CAT#: TA332595

Rabbit anti-ATL1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using ATL1 antibody.

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  Immunofluorescence analysis of A549 cell using ATL1 antibody. Blue: DAPI for nuclear staining

Specifications

Product Data

• Applications: ICC/IF, WB
• Recommended Dilution: WB 1:500 - 1:2000;IF 1:50- 1:200
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human ATL1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 558
• Gene Name: atlastin GTPase 1
• Database Link:
  NP_056999
  Entrez Gene 73991 MouseEntrez Gene 51062 Human
  UniProt ID Q8WXF7
• Background: The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
• Synonyms: AD-FSP; atlastin1; FSP1; GBP3; HSN1D; SPG3; SPG3A

Reference Data

• Protein Families: Druggable Genome, Transmembrane