KDM4C (NM_015061) Human Recombinant Protein

CAT#: TP311182

Recombinant protein of human jumonji domain containing 2C (JMJD2C)

Product Images

Coomassie blue staining of purified KDM4C protein (Cat# TP311182). The protein was produced from HEK293T cells transfected with KDM4C cDNA clone (Cat# RC211182) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC211182. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 119.8 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_055876
• Locus ID: 23081
• UniProt ID: Q9H3R0
• Cytogenetics: 9p24.1
• Refseq Size: 4687
• Refseq ORF: 3168
• Synonyms: GASC1; JHDM3C; JMJD2C; TDRD14C
• Summary: This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
• Protein Families: Druggable Genome, Transcription Factors