ASC2 (PYDC1) (NM_152901) Human Recombinant Protein
CAT#: TP311240
Recombinant protein of human PYD (pyrin domain) containing 1 (PYDC1)
View other "PYDC1" proteins (3)
Special Offer: Get a 20% discount on this product. Use code: "MVPro20".
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
Recombinant protein was produced with TrueORF clone, RC211240. Click on the TrueORF clone link to view cDNA and protein sequences.
|
Tag | C-Myc/DDK |
Predicted MW | 9.9 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_690865 |
Locus ID | 260434 |
UniProt ID | Q8WXC3 |
Cytogenetics | 16p11.2 |
Refseq Size | 582 |
Refseq ORF | 267 |
Synonyms | ASC2; cPOP1; POP1; PYC1 |
Summary | Associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS. [UniProtKB/Swiss-Prot Function] |
Protein Pathways | NOD-like receptor signaling pathway |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC407263 | PYDC1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY407263 | Transient overexpression lysate of PYD (pyrin domain) containing 1 (PYDC1) |
USD 396.00 |
|
PH311240 | PYDC1 MS Standard C13 and N15-labeled recombinant protein (NP_690865) |
USD 2,055.00 |
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