Clusterin (CLU) (NM_001831) Human Recombinant Protein

CAT#: TP311875

Recombinant protein of human clusterin (CLU), transcript variant 1

Product Images

Schematic representation of the conjugation reaction between PEG-functionalized liposomes and the protein CLU via a carboxy-to-amine reaction in the presence of the crosslinker and stabilizer EDC and NHS. CLU Protein CLU from OriGene (TP311875) was used in the conjugation reaction. Figure cited from J Liposome Res, PMID: 28103719

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  Coomassie blue staining of purified CLU protein (Cat# TP311875). The protein was produced from HEK293T cells transfected with CLU cDNA clone (Cat# RC211875) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC211875. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 57.7 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Bioactivity: Probe target (PMID: 28103719)
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001822
• Locus ID: 1191
• UniProt ID: P10909
• Cytogenetics: 8p21.1
• Refseq Size: 2859
• Refseq ORF: 1503
• Synonyms: AAG4; APO-J; APOJ; CLI; CLU1; CLU2; KUB1; NA1/NA2; SGP-2; SGP2; SP-40; TRPM-2; TRPM2
• Summary: 'The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011]'
• Protein Families: Druggable Genome, Secreted Protein