ISCU (NM_014301) Human Recombinant Protein
CAT#: TP312031
Recombinant protein of human iron-sulfur cluster scaffold homolog (E. coli) (ISCU), nuclear gene encoding mitochondrial protein, transcript variant 1
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
Recombinant protein was produced with TrueORF clone, RC212031. Click on the TrueORF clone link to view cDNA and protein sequences.
|
Tag | C-Myc/DDK |
Predicted MW | 15.1 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_055116 |
Locus ID | 23479 |
UniProt ID | Q9H1K1, A0A024RBI3, B3KQ30 |
Cytogenetics | 12q23.3 |
Refseq Size | 1086 |
Refseq ORF | 426 |
Synonyms | 2310020H20Rik; HML; hnifU; ISU2; NIFU; NIFUN |
Summary | This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1. [provided by RefSeq, Feb 2016] |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC403910 | ISCU HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
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LC415371 | ISCU HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC429414 | ISCU HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY403910 | Transient overexpression lysate of iron-sulfur cluster scaffold homolog (E. coli) (ISCU), nuclear gene encoding mitochondrial protein, transcript variant 2 |
USD 396.00 |
|
LY415371 | Transient overexpression lysate of iron-sulfur cluster scaffold homolog (E. coli) (ISCU), nuclear gene encoding mitochondrial protein, transcript variant 1 |
USD 396.00 |
|
LY429414 | Transient overexpression lysate of iron-sulfur cluster scaffold homolog (E. coli) (ISCU), nuclear gene encoding mitochondrial protein, transcript variant 1 |
USD 396.00 |
|
PH312031 | ISCU MS Standard C13 and N15-labeled recombinant protein (NP_055116) |
USD 2,055.00 |
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