FGFR3 (NM_000142) Human Recombinant Protein
CAT#: TP315533
Recombinant protein of human fibroblast growth factor receptor 3 (FGFR3), transcript variant 1
View other "FGFR3" proteins (7)
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
Recombinant protein was produced with TrueORF clone, RC215533. Click on the TrueORF clone link to view cDNA and protein sequences.
|
Tag | C-Myc/DDK |
Predicted MW | 85.7 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_000133 |
Locus ID | 2261 |
UniProt ID | P22607, Q0IJ44 |
Cytogenetics | 4p16.3 |
Refseq Size | 4093 |
Refseq ORF | 2418 |
Synonyms | ACH; CD333; CEK2; HSFGFR3EX; JTK4 |
Summary | 'This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. [provided by RefSeq, Aug 2017]' |
Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
Protein Pathways | Bladder cancer, Endocytosis, MAPK signaling pathway, Pathways in cancer, Regulation of actin cytoskeleton |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC424902 | FGFR3 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LY424902 | Transient overexpression lysate of fibroblast growth factor receptor 3 (FGFR3), transcript variant 1 |
USD 605.00 |
|
PH315533 | FGFR3 MS Standard C13 and N15-labeled recombinant protein (NP_000133) |
USD 2,055.00 |
|
TP700122 | Purified recombinant protein of human fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)(FGFR3), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 µg |
USD 748.00 |
|
TP700123 | Purified recombinant protein of human fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)(FGFR3), transcript variant 2, with C-terminal DDK/His tag, expressed in human cells, 20 µg |
USD 748.00 |
|
TP700124 | Purified recombinant protein of human fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)(FGFR3), transcript variant 3, with C-terminal DDK/His tag, expressed in human cells, 20 µg |
USD 748.00 |
|
TP710033 | Recombinant protein of human fibroblast growth factor receptor 3 (FGFR3), residues 23-375, with C-terminal DDK tag, expressed in sf9 cells. |
USD 425.00 |
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