Prostaglandin D Synthase (PTGDS) (NM_000954) Human Recombinant Protein

CAT#: TP316795

Recombinant protein of human prostaglandin D2 synthase 21kDa (brain) (PTGDS)

Product Images

Coomassie blue staining of purified PTGDS protein (Cat# TP316795). The protein was produced from HEK293T cells transfected with PTGDS cDNA clone (Cat# RC216795) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC216795. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 20.8 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_000945
• Locus ID: 5730
• UniProt ID: P41222, A0A024R8G3
• Cytogenetics: 9q34.3
• Refseq Size: 837
• Refseq ORF: 570
• Synonyms: L-PGDS; LPGDS; PDS; PGD2; PGDS; PGDS2
• Summary: 'The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008]'
• Protein Pathways: Arachidonic acid metabolism, Metabolic pathways