HFE (NM_000410) Human Recombinant Protein

CAT#: TP317447

Recombinant protein of human hemochromatosis (HFE), transcript variant 1

Product Images

Coomassie blue staining of purified HFE protein (Cat# TP317447). The protein was produced from HEK293T cells transfected with HFE cDNA clone (Cat# RC217447) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC217447. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 37.7 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_000401
• Locus ID: 3077
• UniProt ID: Q30201
• Cytogenetics: 6p22.2
• Refseq Size: 2727
• Refseq ORF: 1044
• Synonyms: HFE1; HH; HLA-H; MVCD7; TFQTL2
• Summary: 'The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome, Transmembrane