CNTF (NM_000614) Human Recombinant Protein
CAT#: TP322331
Recombinant protein of human ciliary neurotrophic factor (CNTF)
View other "CNTF" proteins (5)
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
Recombinant protein was produced with TrueORF clone, RC222331. Click on the TrueORF clone link to view cDNA and protein sequences.
|
Tag | C-Myc/DDK |
Predicted MW | 22.8 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_000605 |
Locus ID | 1270 |
UniProt ID | P26441 |
Cytogenetics | 11q12.1 |
Refseq Size | 1891 |
Refseq ORF | 600 |
Synonyms | HCNTF |
Summary | The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010] |
Protein Families | Druggable Genome |
Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC424606 | CNTF HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY424606 | Transient overexpression lysate of ciliary neurotrophic factor (CNTF) |
USD 396.00 |
|
PH322331 | CNTF MS Standard C13 and N15-labeled recombinant protein (NP_000605) |
USD 2,055.00 |
|
TP720608 | Purified recombinant protein of Human ciliary neurotrophic factor (CNTF) |
USD 330.00 |
|
TP723056 | Purified recombinant protein of Human ciliary neurotrophic factor (CNTF). |
USD 240.00 |
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