RUNX1 (NM_001001890) Human Recombinant Protein
CAT#: TP323854
Recombinant protein of human runt-related transcription factor 1 (RUNX1), transcript variant 2
View other "RUNX1" proteins (5)
Special Offer: Get a 20% discount on this product. Use code: "MVPro20".
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
Recombinant protein was produced with TrueORF clone, RC223854. Click on the TrueORF clone link to view cDNA and protein sequences.
|
Tag | C-Myc/DDK |
Predicted MW | 48.6 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Bioactivity | RUNX1 Activity verified in a DNA-binding assay: |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001001890 |
Locus ID | 861 |
UniProt ID | Q01196 |
Cytogenetics | 21q22.12 |
Refseq Size | 7288 |
Refseq ORF | 1359 |
Synonyms | AML1; AML1-EVI-1; AMLCR1; CBF2alpha; CBFA2; EVI-1; PEBP2aB; PEBP2alpha |
Summary | 'Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]' |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors |
Protein Pathways | Acute myeloid leukemia, Chronic myeloid leukemia, Pathways in cancer |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC419764 | RUNX1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LC424261 | RUNX1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LY419764 | Transient overexpression lysate of runt-related transcription factor 1 (RUNX1), transcript variant 1 |
USD 605.00 |
|
LY424261 | Transient overexpression lysate of runt-related transcription factor 1 (RUNX1), transcript variant 2 |
USD 605.00 |
|
PH323854 | RUNX1 MS Standard C13 and N15-labeled recombinant protein (NP_001001890) |
USD 2,055.00 |
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