FLIP (CFLAR) (NM_001127184) Human Recombinant Protein
CAT#: TP325270
Recombinant protein of human CASP8 and FADD-like apoptosis regulator (CFLAR), transcript variant 3
View other "CFLAR" proteins (7)
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
Recombinant protein was produced with TrueORF clone, RC225270. Click on the TrueORF clone link to view cDNA and protein sequences.
|
Tag | C-Myc/DDK |
Predicted MW | 25.2 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001120656 |
Locus ID | 8837 |
UniProt ID | O15519 |
Cytogenetics | 2q33.1 |
Refseq ORF | 663 |
Synonyms | c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; CASH; CASP8AP1; Casper; cFLIP; CLARP; FLAME; FLAME-1; FLAME1; FLIP; I-FLICE; MRIT |
Summary | The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011] |
Protein Families | Druggable Genome, Protease |
Protein Pathways | Apoptosis |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC418376 | CFLAR HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC426693 | CFLAR HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC426694 | CFLAR HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY418376 | Transient overexpression lysate of CASP8 and FADD-like apoptosis regulator (CFLAR), transcript variant 1 |
USD 396.00 |
|
LY426693 | Transient overexpression lysate of CASP8 and FADD-like apoptosis regulator (CFLAR), transcript variant 2 |
USD 396.00 |
|
LY426694 | Transient overexpression lysate of CASP8 and FADD-like apoptosis regulator (CFLAR), transcript variant 3 |
USD 396.00 |
|
PH325270 | CFLAR MS Standard C13 and N15-labeled recombinant protein (NP_001120656) |
USD 2,055.00 |
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