Cgas (NM_173386) Mouse Recombinant Protein

CAT#: TP513022

Purified recombinant protein of Mouse cyclic GMP-AMP synthase (Cgas), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug


USD 748.00

4 Weeks*

Size
    • 20 ug

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Specifications

Product Data
Species Mouse
Expression Host HEK293T
Expression cDNA Clone or AA Sequence
A DNA sequence from Mouse cDNA ORF Clone, MR213022, encoding Mouse full-length Cgas.
Tag C-MYC/DDK
Predicted MW 58.2 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_775562
Locus ID 214763
UniProt ID Q8C6L5, Q8BSY1
Cytogenetics 9 E1
Refseq Size 4090
Refseq ORF 1524
Synonyms E330016A19Rik; Mb21d1
Summary The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.