TNFRSF14 (NM_003820) Human Recombinant Protein

CAT#: TP700280

Purified recombinant protein of human tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14), with C-terminal DDK/His tag, expressed in human cells, 20 µg


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USD 748.00

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Size
    • 20 ug

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Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC201167, encoding the region (Leu39 – Val202) of human TNFRSF14
Tag C-DDK/His
Predicted MW 19 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH7.4, 10% glycerol
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_003811
Locus ID 8764
UniProt ID Q92956, A0A024R052
Cytogenetics 1p36.32
Refseq Size 3519
Refseq ORF 849
Synonyms ATAR; CD270; HVEA; HVEM; LIGHTR; TR2
Summary This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction

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