BCMA (TNFRSF17) (NM_001192) Human Recombinant Protein

CAT#: TP700293

Purified recombinant protein of human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17), with C-terminal Fc tag, expressed in human cells, 20 µg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, RC208851, encoding the region (Met1 – Ala54) of human TNFRSF17
• Tag: C-Fc
• Predicted MW: 33 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: PBS, pH7.4, 10% glycerol
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001183
• Locus ID: 608
• UniProt ID: Q02223
• Cytogenetics: 16p13.13
• Refseq Size: 994
• Refseq ORF: 552
• Synonyms: BCM; BCMA; CD269; TNFRSF13A
• Summary: 'The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction