Alpha 2 Antiplasmin (SERPINF2) (NM_000934) Human Recombinant Protein

CAT#: TP701066

Purified recombinant protein of Human serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 (SERPINF2), with C-terminal His tag, secretory expressed in HEK293 cells, 50ug


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USD 748.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC206435, encoding the region Met28-Lys491 of SERPINF2
Tag C-His
Predicted MW 53 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS,pH7.4,10% glycerol;
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000925
Locus ID 5345
UniProt ID P08697
Cytogenetics 17p13.3
Refseq Size 2284
Refseq ORF 1473
Synonyms A2AP; AAP; ALPHA-2-PI; API; PLI
Summary 'This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]'
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Complement and coagulation cascades

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