CD47 (NM_001777) Human Recombinant Protein

CAT#: TP710231

Purified recombinant protein of Human CD47 molecule (CD47), transcript variant 1, residues 19-141aa, with C-terminal DDK tag, expressed in sf9, 20ug


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USD 425.00

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Size
    • 20 ug

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Specifications

Product Data
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC218813, the region(Met-Gln19-Glu141) of Homo sapiens CD47
Tag C-DDK
Predicted MW 14 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001768
Locus ID 961
UniProt ID Q08722
Cytogenetics 3q13.12
Refseq Size 5346
Refseq ORF 969
Synonyms IAP; MER6; OA3
Summary This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
Protein Families Druggable Genome, Transmembrane
Protein Pathways ECM-receptor interaction

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