BMP2 (NM_001200) Human Recombinant Protein

CAT#: TP720011

Recombinant protein of human bone morphogenetic protein 2 (BMP2), the domain of Gln283-Arg396


  View other "BMP2" proteins (5)

USD 330.00

3 Weeks*

Size
    • 10 ug

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Frequently bought together (1)
Rabbit Polyclonal BMP-2 Antibody
    • 100 ul

USD 424.00

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Tag tag free
Predicted MW 13 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 10mM HAc-NH4Ac, 4% D-Mannitol, pH4.0.
Bioactivity ED50 is less than 50 ng/ml as determined by the cytolysis of MC3T3-E1 cells. Specific Activity of 2.0 x 104 IU/mg
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_001191
Locus ID 650
UniProt ID P12643, C8C060
Cytogenetics 20p12.3
Synonyms BDA2; BMP2A; SSFSC; SSFSC1
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016]
Protein Families Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transmembrane
Protein Pathways Acute myeloid leukemia, Basal cell carcinoma, Cytokine-cytokine receptor interaction, Endocytosis, Hedgehog signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, TGF-beta signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.