Carbonic Anhydrase I (CA1) (NM_001128829) Human Recombinant Protein

CAT#: TP720088

Recombinant protein of human carbonic anhydrase I (CA1), transcript variant 1

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Ala2-Phe261
• Tag: C-His
• Predicted MW: 30 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Supplied as a 0.2 um filtered solution of 12.5mM Tris HCl,75mM NaCl,pH 7.5.
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Storage: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_001122301
• Locus ID: 759
• UniProt ID: P00915, V9HWE3
• Cytogenetics: 8q21.2
• Synonyms: CA-I; CAB; Car1; HEL-S-11
• Summary: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Nov 2016]
• Protein Families: Druggable Genome
• Protein Pathways: Nitrogen metabolism