PPCDC (NM_021823) Human Recombinant Protein
CAT#: TP720225L
Recombinant protein of human phosphopantothenoylcysteine decarboxylase (PPCDC)
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Ser204
|
Tag | N-His |
Predicted MW | 24.6 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 50mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_068595 |
Locus ID | 60490 |
UniProt ID | Q96CD2 |
Cytogenetics | 15q24.2 |
Synonyms | coaC; MDS018; PPC-DC |
Summary | Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM, Mar 2008] |
Protein Pathways | Metabolic pathways, Pantothenate and CoA biosynthesis |
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