Osteoprotegerin (TNFRSF11B) (NM_002546) Human Recombinant Protein

CAT#: TP720285

Recombinant protein of human tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B)


  View other "Osteoprotegerin" proteins (3)

USD 330.00

3 Weeks*

Size
    • 10 ug

Product Images

Frequently bought together (1)
Mouse Monoclonal Osteoprotegerin/TNFRSF11B Antibody (98A1071)
    • 100 ug

USD 457.00

Other products for "Osteoprotegerin"

Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Tag C-His
Predicted MW 44.7 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_002537
Locus ID 4982
UniProt ID O00300
Cytogenetics 8q24.12
Synonyms OCIF; OPG; PDB5; TR1
Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction

Documents

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.