TIMP1 (NM_003254) Human Recombinant Protein
CAT#: TP720383
Recombinant protein of human TIMP metallopeptidase inhibitor 1 (TIMP1)
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Cys24-Ala207
|
Tag | N-His |
Predicted MW | 21.7 kDa |
Concentration | Resuspend the protein to the desired concentration in proper buffer. |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.2. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_003245 |
Locus ID | 7076 |
UniProt ID | P01033, Q6FGX5 |
Cytogenetics | Xp11.3 |
Synonyms | CLGI; EPA; EPO; HCI; TIMP; TIMP-1 |
Summary | 'This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]' |
Protein Families | Druggable Genome, Secreted Protein |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC418808 | TIMP1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 99.00 |
|
LY418808 | Transient overexpression lysate of TIMP metallopeptidase inhibitor 1 (TIMP1) |
USD 325.00 |
|
TP723447 | Purified recombinant protein of Human TIMP metallopeptidase inhibitor 1 (TIMP1). |
USD 240.00 |
|
TP723878 | Purified recombinant protein of Human TIMP metallopeptidase inhibitor 1 (TIMP1) |
USD 270.00 |
|
TP761577 | Purified recombinant protein of Human TIMP metallopeptidase inhibitor 1 (TIMP1), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug |
USD 215.00 |
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