GDNF Receptor alpha 1 (GFRA1) (NM_001145453) Human Recombinant Protein
CAT#: TP720395
Recombinant protein of human GDNF family receptor alpha 1 (GFRA1), transcript variant 3
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Asp25-Lys429
|
Tag | C-His |
Predicted MW | 46.3 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_001138925 |
Locus ID | 2674 |
UniProt ID | P56159 |
Cytogenetics | 10q25.3 |
Synonyms | GDNFR; GDNFRA; GFR-ALPHA-1; GFRalpha-1; RET1L; RETL1; TRNR1 |
Summary | This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016] |
Protein Families | Druggable Genome |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC407880 | GFRA1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC417417 | GFRA1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LC428898 | GFRA1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY407880 | Transient overexpression lysate of GDNF family receptor alpha 1 (GFRA1), transcript variant 2 |
USD 396.00 |
|
LY417417 | Transient overexpression lysate of GDNF family receptor alpha 1 (GFRA1), transcript variant 1 |
USD 605.00 |
|
LY428898 | Transient overexpression lysate of GDNF family receptor alpha 1 (GFRA1), transcript variant 3 |
USD 396.00 |
|
PH326704 | GFRA1 MS Standard C13 and N15-labeled recombinant protein (NP_001138925) |
USD 2,055.00 |
|
TP326704 | Recombinant protein of human GDNF family receptor alpha 1 (GFRA1), transcript variant 3 |
USD 788.00 |
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