PEDF (SERPINF1) (NM_002615) Human Recombinant Protein
CAT#: TP720443L
Recombinant protein of human serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (SERPINF1)
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Gln20-Pro418
|
Tag | C-His |
Predicted MW | 45.4 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_002606 |
Locus ID | 5176 |
UniProt ID | P36955, A0A140VKF3 |
Cytogenetics | 17p13.3 |
Synonyms | EPC-1; OI6; OI12; PEDF; PIG35 |
Summary | This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI. [provided by RefSeq, Aug 2016] |
Protein Families | Druggable Genome, Secreted Protein |
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