SPINT2 (NM_021102) Human Recombinant Protein

CAT#: TP720702

Purified recombinant protein of Human serine peptidase inhibitor, Kunitz type, 2 (SPINT2), transcript variant a

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Ala28-Lys197
• Tag: C-His
• Predicted MW: 20.22 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH8.0.
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_066925
• Locus ID: 10653
• UniProt ID: O43291, B4DLU1
• Cytogenetics: 19q13.2
• Refseq Size: 1817
• Refseq ORF: 756
• Synonyms: DIAR3; HAI-2; HAI2; Kop; PB
• Summary: This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
• Protein Families: Transmembrane