HIP2 (UBE2K) (NM_005339) Human Recombinant Protein

CAT#: TP720982

Purified recombinant protein of Human ubiquitin-conjugating enzyme E2K (UBE2K), transcript variant 1


  View other "HIP2" proteins (7)

USD 330.00

3 Weeks*

Size
    • 10 ug

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Frequently bought together (1)
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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Tag N-His&SUMO
Predicted MW 34.5 kDa
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_005330
Locus ID 3093
UniProt ID P61086
Cytogenetics 4p14
Refseq Size 2208
Refseq ORF 600
Synonyms E2-25K; HIP2; HYPG; LIG; UBC1
Summary The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Ubiquitin mediated proteolysis

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.