TPP1 (NM_000391) Human Recombinant Protein

CAT#: TP721045

Purified recombinant protein of Human tripeptidyl peptidase I (TPP1)


  View other "TPP1" proteins (2)

USD 330.00

3 Weeks*

Size
    • 10 ug

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Frequently bought together (1)
Rabbit Polyclonal antibody to TPP1 (tripeptidyl peptidase I)
    • 100 ul

USD 415.00

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Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Tag C-His
Predicted MW 23.94 kDa
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM CaCl2, 10% Glycerol, pH 7.5.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_000382
Locus ID 1200
UniProt ID O14773
Cytogenetics 11p15.4
Refseq Size 3540
Refseq ORF 1689
Synonyms CLN2; GIG1; LPIC; SCAR7; TPP-1
Summary This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]
Protein Families Protease
Protein Pathways Lysosome

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.