ERp57 (PDIA3) (NM_005313) Human Recombinant Protein
CAT#: TP721117
Purified recombinant protein of Human protein disulfide isomerase family A, member 3 (PDIA3
Product Images
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Ser25-Leu505
|
Tag | C-His |
Predicted MW | 55.3 kDa |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_005304 |
Locus ID | 2923 |
UniProt ID | P30101, V9HVY3 |
Cytogenetics | 15q15.3 |
Refseq Size | 3060 |
Refseq ORF | 1515 |
Synonyms | ER60; ERp57; ERp60; ERp61; GRP57; GRP58; HEL-S-93n; HEL-S-269; HsT17083; P58; PI-PLC |
Summary | This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates. [provided by RefSeq, Dec 2016] |
Protein Families | Druggable Genome |
Protein Pathways | Antigen processing and presentation |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC401637 | PDIA3 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY401637 | Transient overexpression lysate of protein disulfide isomerase family A, member 3 (PDIA3) |
USD 396.00 |
|
PH305940 | PDIA3 MS Standard C13 and N15-labeled recombinant protein (NP_005304) |
USD 2,055.00 |
|
TP305940 | Recombinant protein of human protein disulfide isomerase family A, member 3 (PDIA3) |
USD 823.00 |
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