PPT1 (NM_000310) Human Recombinant Protein

CAT#: TP760080

Recombinant protein of human palmitoyl-protein thioesterase 1 (PPT1), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length PPT1
Tag N-His
Predicted MW 34.2 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000301
Locus ID 5538
UniProt ID P50897
Cytogenetics 1p34.2
Refseq Size 2504
Refseq ORF 918
Synonyms CLN1; INCL; PPT
Summary 'The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2008]'
Protein Families Druggable Genome
Protein Pathways Fatty acid elongation in mitochondria, Lysosome, Metabolic pathways

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