TFEC (NM_001018058) Human Recombinant Protein
CAT#: TP760879
Purified recombinant protein of Human transcription factor EC (TFEC), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Other products for "TFEC"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length TFEC
|
Tag | N-His |
Predicted MW | 35.4 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001018068 |
Locus ID | 22797 |
UniProt ID | O14948 |
Cytogenetics | 7q31.2 |
Refseq Size | 6544 |
Refseq ORF | 954 |
Synonyms | bHLHe34; hTFEC-L; TCFEC; TFE-C; TFEC-L; TFECL |
Summary | This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] |
Protein Families | Druggable Genome, Transcription Factors |
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