Deoxyguanosine kinase (DGUOK) (NM_080918) Human Recombinant Protein
CAT#: TP760996
Purified recombinant protein of Human deoxyguanosine kinase (DGUOK), nuclear gene encoding mitochondrial protein, transcript variant 2, full length, with N-terminal HIS tag, expressed in E.coli, 50ug
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length DGUOK
|
Tag | N-His |
Predicted MW | 17.3 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, 8M Urea, pH8.0 |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_550440 |
Locus ID | 1716 |
UniProt ID | Q16854, E5KSL6 |
Cytogenetics | 2p13.1 |
Refseq Size | 880 |
Refseq ORF | 567 |
Synonyms | dGK; MTDPS3; NCPH; PEOB4 |
Summary | 'In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]' |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Purine metabolism |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC409002 | DGUOK HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC409003 | DGUOK HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY409002 | Transient overexpression lysate of deoxyguanosine kinase (DGUOK), nuclear gene encoding mitochondrial protein, transcript variant 1 |
USD 396.00 |
|
LY409003 | Transient overexpression lysate of deoxyguanosine kinase (DGUOK), nuclear gene encoding mitochondrial protein, transcript variant 2 |
USD 396.00 |
|
PH304891 | DGUOK MS Standard C13 and N15-labeled recombinant protein (NP_550438) |
USD 2,055.00 |
|
TP304891 | Recombinant protein of human deoxyguanosine kinase (DGUOK), nuclear gene encoding mitochondrial protein, transcript variant 1 |
USD 823.00 |
{0} Product Review(s)
Be the first one to submit a review