PTPN20A (NM_001042389) Human Recombinant Protein

CAT#: TP761051

Purified recombinant protein of Human protein tyrosine phosphatase, non-receptor type 20A (PTPN20A), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Tag: N-His
• Predicted MW: 48.2 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Reference Data

• RefSeq: NP_001035848
• Locus ID: 653129
• Cytogenetics: 10q11.22
• Refseq Size: 2965
• Refseq ORF: 1260
• Synonyms: bA142I17.1; CT126; hPTPN20; PTPN20B
• Summary: The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more centromeric copy, PTPN20A. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome