XAF1 (NM_017523) Human Recombinant Protein

CAT#: TP761295

Purified recombinant protein of Human XIAP associated factor 1 (XAF1), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length XAF1
Tag N-GST and C-His
Predicted MW 62.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1%Sarkosyl.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_059993
Locus ID 54739
UniProt ID Q6GPH4
Cytogenetics 17p13.1
Refseq Size 3638
Refseq ORF 903
Synonyms BIRC4BP; HSXIAPAF1; XIAPAF1
Summary This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

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