APRIL (TNFSF13) (NM_172088) Human Recombinant Protein
CAT#: TP761373
Purified recombinant protein of Human tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13), transcript variant gamma, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length TNFSF13
|
Tag | N-GST and C-His |
Predicted MW | 52.9 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1% Sarkosyl. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_742085 |
Locus ID | 8741 |
UniProt ID | O75888 |
Cytogenetics | 17p13.1 |
Refseq Size | 2112 |
Refseq ORF | 741 |
Synonyms | APRIL; CD256; TALL-2; TALL2; TNLG7B; TRDL-1; UNQ383/PRO715; ZTNF2 |
Summary | The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010] |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC401250 | TNFSF13 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC406830 | TNFSF13 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC434048 | TNFSF13 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY401250 | Transient overexpression lysate of tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13), transcript variant alpha |
USD 396.00 |
|
LY406830 | Transient overexpression lysate of tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13), transcript variant gamma |
USD 396.00 |
|
LY434048 | Transient overexpression lysate of tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13), transcript variant eta |
USD 396.00 |
|
TP723020 | Purified recombinant protein of Human tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13), transcript variant alpha. |
USD 240.00 |
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