MITF (NM_000248) Human Recombinant Protein
CAT#: TP761494
Purified recombinant protein of Human microphthalmia-associated transcription factor (MITF), transcript variant 4, full length, with N-terminal HIS tag, expressed in E.coli, 50ug
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length MITF
|
Tag | N-His |
Predicted MW | 46.8 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1% Sarkosyl. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_000239 |
Locus ID | 4286 |
UniProt ID | O75030 |
Cytogenetics | 3p13 |
Refseq Size | 4490 |
Refseq ORF | 1257 |
Synonyms | bHLHe32; CMM8; COMMAD; MI; WS2; WS2A |
Summary | 'The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]' |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Melanogenesis, Melanoma, Pathways in cancer |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC404984 | MITF HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LC424990 | MITF HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY404984 | Transient overexpression lysate of microphthalmia-associated transcription factor (MITF), transcript variant 6 |
USD 605.00 |
|
LY424990 | Transient overexpression lysate of microphthalmia-associated transcription factor (MITF), transcript variant 4 |
USD 396.00 |
|
TP761396 | Purified recombinant protein of Human microphthalmia-associated transcription factor (MITF), transcript variant 5, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug |
USD 215.00 |
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