ZBTB4 (NM_020899) Human Recombinant Protein

CAT#: TP762183

Purified recombinant protein of Human zinc finger and BTB domain containing 4 (ZBTB4), transcript variant 1, Ala788-End, with N-terminal His-PDCD1(Pro21-Val170) tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein ZBTB4 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Ala788-End) of ZBTB4
• Tag: N-His PDCD1(Pro21-Val170)
• Predicted MW: 39.2 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, 8M Urea, pH8.0.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_065950
• Locus ID: 57659
• UniProt ID: Q9P1Z0, B3KVD4
• Cytogenetics: 17p13.1
• Refseq Size: 5961
• Refseq ORF: 3039
• Synonyms: KAISO-L1; ZNF903
• Summary: Transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA (PubMed:16354688). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal. [UniProtKB/Swiss-Prot Function]