PMS1 (NM_000534) Human Recombinant Protein

CAT#: TP762279

Purified recombinant protein of Human PMS1 postmeiotic segregation increased 1 (S. cerevisiae) (PMS1), transcript variant 1, Glu323-Ser423, with N-terminal His-ABP tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein PMS1 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Glu323-Ser423) of PMS1
• Tag: N-His ABP
• Predicted MW: 26.3 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_000525
• Locus ID: 5378
• UniProt ID: P54277
• Cytogenetics: 2q32.2
• Refseq Size: 3239
• Refseq ORF: 2796
• Synonyms: HNPCC3; hPMS1; MLH2; PMSL1
• Summary: 'This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome, Transcription Factors