Bile Acid Receptor (NR1H4) (NM_005123) Human Recombinant Protein

CAT#: TP762280

Purified recombinant protein of Human nuclear receptor subfamily 1, group H, member 4 (NR1H4), transcript variant 2, Phe21-Val297, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein NR1H4 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Phe21-Val297) of NR1H4
• Tag: N-His
• Predicted MW: 31.8 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_005114
• Locus ID: 9971
• UniProt ID: Q96RI1, B6ZGS9
• Cytogenetics: 12q23.1
• Refseq Size: 2218
• Refseq ORF: 1416
• Synonyms: BAR; FXR; HRR-1; HRR1; PFIC5; RIP14
• Summary: This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2016]
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors