Cytochrome P450 26B (CYP26B1) (NM_019885) Human Recombinant Protein

CAT#: TP762329

Purified recombinant protein of Human cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1), Pro229-End, with N-terminal His tag, expressed in E.coli, 50ug


USD 205.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Pro229-End) of CYP26B1
Tag N-His
Predicted MW 31.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, pH8.0, 8M Urea
Storage Store at -80°C after receiving vials.
Stability Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_063938
Locus ID 56603
UniProt ID Q9NR63
Cytogenetics 2p13.2
Refseq Size 4567
Refseq ORF 1536
Synonyms CYP26A2; P450RAI-2; P450RAI2; RHFCA
Summary This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
Protein Families Druggable Genome, P450
Protein Pathways Retinol metabolism

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.