IRE1 (ERN2) (NM_033266) Human Recombinant Protein
CAT#: TP762684
Purified recombinant protein of Human endoplasmic reticulum to nucleus signaling 2 (ERN2), full length, with N-GST and C-His tag, expressed in E.coli, 50ug
Other products for "ERN2"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region full length of ERN2
|
Tag | N-GST and C-HIS |
Predicted MW | 135.2 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, pH8.0, 8M Urea |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_150296 |
Locus ID | 10595 |
UniProt ID | Q76MJ5, A5YM46, A5YM65 |
Cytogenetics | 16p12.2 |
Refseq Size | 3549 |
Refseq ORF | 2922 |
Synonyms | hIRE2p; IRE1-BETA; IRE1b; IRE2p |
Summary | Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.[UniProtKB/Swiss-Prot Function] |
Protein Families | Druggable Genome, Protein Kinase |
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