Cyclin F (CCNF) (NM_001761) Human Recombinant Protein

CAT#: TP762696

Purified recombinant protein of Human cyclin F (CCNF), full length, with N-GST and C-His tag, expressed in E.coli, 50ug


USD 261.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region full length of CCNF
Tag N-GST and C-HIS
Predicted MW 115.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, pH8.0, 8M Urea
Storage Store at -80°C after receiving vials.
Stability Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001752
Locus ID 899
UniProt ID P41002, Q59HD0
Cytogenetics 16p13.3
Refseq Size 4287
Refseq ORF 2358
Synonyms FBX1; FBXO1; FTDALS5
Summary This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome

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