CD51 (ITGAV) Human shRNA Lentiviral Particle (Locus ID 3685)

CAT#: TL312085V

ITGAV - Human shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.

Product Images

GFP signal was observed under microscope at 48 hours after transduction of TL312085A virus into HEK293 cells. TL312085A virus was prepared using lenti-shRNA TL312085A and TR30037 packaging kit.

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  GFP signal was observed under microscope at 48 hours after transduction of TL312085A virus into HEK293 cells. TL312085A virus was prepared using lenti-shRNA TL312085A and TR30037 packaging kit.

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  GFP signal was observed under microscope at 48 hours after transduction of TL312085A virus into HEK293 cells. TL312085A virus was prepared using lenti-shRNA TL312085A and TR30037 packaging kit.

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  GFP signal was observed under microscope at 48 hours after transduction of TL312085B virus into HEK293 cells. TL312085B virus was prepared using lenti-shRNA TL312085B and TR30037 packaging kit.

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  GFP signal was observed under microscope at 48 hours after transduction of TL312085B virus into HEK293 cells. TL312085B virus was prepared using lenti-shRNA TL312085B and TR30037 packaging kit.

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  GFP signal was observed under microscope at 48 hours after transduction of TL312085B virus into HEK293 cells. TL312085B virus was prepared using lenti-shRNA TL312085B and TR30037 packaging kit.

• GFP signal was observed under microscope at 48 hours after transduction of [TL312085C] virus into HEK293 cells. [TL312085C] virus was prepared using lenti-shRNA [TL312085C] and TR30037 packaging kit.

• GFP signal was observed under microscope at 48 hours after transduction of [TL312085C] virus into HEK293 cells. [TL312085C] virus was prepared using lenti-shRNA [TL312085C] and TR30037 packaging kit.

• GFP signal was observed under microscope at 48 hours after transduction of [TL312085C] virus into HEK293 cells. [TL312085C] virus was prepared using lenti-shRNA [TL312085C] and TR30037 packaging kit.

• GFP signal was observed under microscope at 48 hours after transduction of [TL312085D] virus into HEK293 cells. [TL312085D] virus was prepared using lenti-shRNA [TL312085D] and TR30037 packaging kit.

• GFP signal was observed under microscope at 48 hours after transduction of [TL312085D] virus into HEK293 cells. [TL312085D] virus was prepared using lenti-shRNA [TL312085D] and TR30037 packaging kit.

• GFP signal was observed under microscope at 48 hours after transduction of [TL312085D] virus into HEK293 cells. [TL312085D] virus was prepared using lenti-shRNA [TL312085D] and TR30037 packaging kit.

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Specifications

Product Data

• Locus ID: 3685
• Synonyms: CD51; MSK8; VNRA; VTNR
• Vector: pGFP-C-shLenti
• Format: Lentiviral particles
• RefSeq: NM_001144999, NM_001145000, NM_002210, NM_002210.1, NM_002210.3, NM_002210.4, NM_001144999.1, NM_001144999.2, NM_001145000.1, NM_001145000.2, BC047454, BC072686, BC126231, BC136442, BC144100
• UniProt ID: P06756
• Summary: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Performance Guaranteed: OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples.
  
  For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred).