NEK11 Human siRNA Oligo Duplex (Locus ID 79858)

CAT#: SR312655

NEK11 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each

Specifications

Product Data

• Purity: HPLC purified
• Quality Control: Tested by ESI-MS
• Sequences: Available with shipment
• Components: NEK11 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 79858)
  Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
• Stability: One year from date of shipment when stored at -20°C.
• Number of Transfections: Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).
• Note: Single siRNA duplex (10nmol) can be ordered.

Reference Data

• RefSeq: NM_001146003, NM_001321220, NM_001321221, NM_001321222, NM_001321223, NM_001321224, NM_024800, NM_145910, NM_001353022, NM_001353023, NM_001353024, NM_001353025, NM_001353026, NM_001353027, NM_001353028, NM_001353029, NM_001353030, NM_001353031, NM_001353032, NM_001353033, NM_001353034, NM_001353036, NM_001353037, NM_001353038, NM_001353039, NM_001353040, NM_001353041, NM_001353042, NM_001353043, NM_001353044, NM_001353045, NM_001353046, NM_001353048
• Synonyms: FLJ23495
• Summary: This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
• Performance Guaranteed: OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.
  
  For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).