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Target Symbol
- CANX (5)
- PCNA (4)
- TP53 (4)
- ADAMTS1 (3)
- CELSR3 (3)
- ENPP3 (3)
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- GPR4 (3)
- HSP90AB1 (3)
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- WNT10A (2)
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- AAMP (1)
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Applications
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Knockout (KO) Validation
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Families
- Druggable Genome (342)
- Transmembrane (254)
- GPCR (108)
- Secreted Protein (40)
- ES Cell Differentiation/IPS (31)
- Stem cell - Pluripotency (31)
- Transcription Factors (30)
- Protease (18)
- Protein Kinase (12)
- Cancer stem cells (10)
- Adult stem cells (6)
- Induced pluripotent stem cells (6)
- Ion Channels: Potassium (6)
- Nuclear Hormone Receptor (6)
- Embryonic stem cells (5)
- P450 (5)
- Ion Channels: Transient receptor potential (4)
- Stem cell relevant signaling - Wnt Signaling pathway (4)
- Ion Channels: Other (3)
- Ion Channels: ATP Receptors (2)
- Phosphatase (2)
- Ion Channels: Calcium (1)
- Ion Channels: Sodium (1)
Pathways
- Neuroactive ligand-receptor interaction (74)
- Metabolic pathways (42)
- Pathways in cancer (39)
- Calcium signaling pathway (36)
- Wnt signaling pathway (23)
- Basal cell carcinoma (20)
- MAPK signaling pathway (19)
- Hedgehog signaling pathway (18)
- Melanogenesis (18)
- Cytokine-cytokine receptor interaction (16)
- Progesterone-mediated oocyte maturation (16)
- Antigen processing and presentation (15)
- Chemokine signaling pathway (15)
- Alzheimer's disease (14)
- Prostate cancer (14)
- Vascular smooth muscle contraction (14)
- Cell cycle (13)
- Huntington's disease (13)
- Purine metabolism (13)
- Regulation of actin cytoskeleton (13)
- Focal adhesion (12)
- Parkinson's disease (12)
- Colorectal cancer (10)
- Amyotrophic lateral sclerosis (ALS) (9)
- Endocytosis (9)
- NOD-like receptor signaling pathway (9)
- Prion diseases (9)
- VEGF signaling pathway (9)
- Apoptosis (8)
- Fc epsilon RI signaling pathway (8)
- Gap junction (8)
- Glycolysis / Gluconeogenesis (8)
- Hematopoietic cell lineage (8)
- Neurotrophin signaling pathway (8)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (7)
- Chronic myeloid leukemia (7)
- Fc gamma R-mediated phagocytosis (7)
- Glioma (7)
- Leukocyte transendothelial migration (7)
- Non-small cell lung cancer (7)
- Pancreatic cancer (7)
- Small cell lung cancer (7)
- T cell receptor signaling pathway (7)
- Tight junction (7)
- Toll-like receptor signaling pathway (7)
- p53 signaling pathway (7)
- Adherens junction (6)
- Androgen and estrogen metabolism (6)
- B cell receptor signaling pathway (6)
- Cell adhesion molecules (CAMs) (6)
- Dilated cardiomyopathy (6)
- Endometrial cancer (6)
- GnRH signaling pathway (6)
- Hypertrophic cardiomyopathy (HCM) (6)
- Melanoma (6)
- Natural killer cell mediated cytotoxicity (6)
- Renal cell carcinoma (6)
- Adipocytokine signaling pathway (5)
- C21-Steroid hormone metabolism (5)
- Complement and coagulation cascades (5)
- DNA replication (5)
- Insulin signaling pathway (5)
- Mismatch repair (5)
- PPAR signaling pathway (5)
- Pathogenic Escherichia coli infection (5)
- Viral myocarditis (5)
- Base excision repair (4)
- Bladder cancer (4)
- Cardiac muscle contraction (4)
- ErbB signaling pathway (4)
- Glutathione metabolism (4)
- Jak-STAT signaling pathway (4)
- Long-term depression (4)
- Long-term potentiation (4)
- Nicotinate and nicotinamide metabolism (4)
- Nucleotide excision repair (4)
- Oocyte meiosis (4)
- Starch and sucrose metabolism (4)
- Thyroid cancer (4)
- mTOR signaling pathway (4)
- Acute myeloid leukemia (3)
- Arachidonic acid metabolism (3)
- Autoimmune thyroid disease (3)
- Cysteine and methionine metabolism (3)
- ECM-receptor interaction (3)
- Epithelial cell signaling in Helicobacter pylori infection (3)
- Lysosome (3)
- Metabolism of xenobiotics by cytochrome P450 (3)
- Oxidative phosphorylation (3)
- Pantothenate and CoA biosynthesis (3)
- RNA degradation (3)
- Riboflavin metabolism (3)
- Ribosome (3)
- Spliceosome (3)
- Type II diabetes mellitus (3)
- Ubiquitin mediated proteolysis (3)
- Vibrio cholerae infection (3)
- ABC transporters (2)
- Allograft rejection (2)
- Arginine and proline metabolism (2)
- Asthma (2)
- Axon guidance (2)
- Basal transcription factors (2)
- Caffeine metabolism (2)
- Citrate cycle (TCA cycle) (2)
- Drug metabolism - other enzymes (2)
- Fructose and mannose metabolism (2)
- Olfactory transduction (2)
- Phosphatidylinositol signaling system (2)
- Pyruvate metabolism (2)
- RIG-I-like receptor signaling pathway (2)
- Selenoamino acid metabolism (2)
- Sphingolipid metabolism (2)
- Systemic lupus erythematosus (2)
- Taste transduction (2)
- Alanine (1)
- Amino sugar and nucleotide sugar metabolism (1)
- Dorso-ventral axis formation (1)
- Drug metabolism - cytochrome P450 (1)
- Ether lipid metabolism (1)
- Glycerolipid metabolism (1)
- Glycerophospholipid metabolism (1)
- Inositol phosphate metabolism (1)
- Linoleic acid metabolism (1)
- Maturity onset diabetes of the young (1)
- N-Glycan biosynthesis (1)
- Non-homologous end-joining (1)
- Notch signaling pathway (1)
- O-Glycan biosynthesis (1)
- One carbon pool by folate (1)
- Pentose phosphate pathway (1)
- Phenylalanine (1)
- Phenylalanine metabolism (1)
- Primary immunodeficiency (1)
- Pyrimidine metabolism (1)
- Renin-angiotensin system (1)
- Retinol metabolism (1)
- TGF-beta signaling pathway (1)
- Tryptophan metabolism (1)
- Type I diabetes mellitus (1)
- Tyrosine metabolism (1)
- alpha-Linolenic acid metabolism (1)
- aspartate and glutamate metabolism (1)
- tyrosine and tryptophan biosynthesis (1)