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- IgG2b
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Target Symbol
- MAP2K1 (27)
- MAP2K3 (21)
- NPR3 (17)
- RAB21 (17)
- DNM1L (14)
- ERBB2 (12)
- PIK3R5 (12)
- ACAA2 (10)
- BRDU (10)
- BSG (10)
- LTA4H (10)
- MDM4 (10)
- NME1 (10)
- OTC (10)
- SLA2 (10)
- TP53 (10)
- ABCB1 (8)
- AGR2 (8)
- KIT (8)
- LIPG (8)
- MSMB (8)
- OXSM (8)
- PCNA (8)
- PMEL (8)
- RARRES1 (8)
- SYT4 (8)
- BCL2 (7)
- CD4 (7)
- CTNNB1 (7)
- GBP2 (7)
- PRKCE (7)
- SAMHD1 (7)
- TUBAL3 (7)
- ALOX15 (6)
- APOE (6)
- CD99 (6)
- CDC123 (6)
- CYP2A6 (6)
- DHRS4L2 (6)
- EPCAM (6)
- EPHX1 (6)
- ESR1 (6)
- FAHD2A (6)
- JUN (6)
- KLK8 (6)
- LGALS3 (6)
- MAPK13 (6)
- MCM2 (6)
- NAPSA (6)
- PIK3C2A (6)
- TBC1D21 (6)
- TSC22D1 (6)
- ACAT2 (5)
- BTLA (5)
- CBWD1 (5)
- CRYAA (5)
- CYP1A2 (5)
- PLK1 (5)
- PMS2 (5)
- SERPINB1 (5)
- SOX17 (5)
- SYP (5)
- TG (5)
- ACSS2 (4)
- ADIPOQ (4)
- AMDHD1 (4)
- APP (4)
- ASH2L (4)
- BFSP1 (4)
- CD40 (4)
- CD68 (4)
- CEACAM5 (4)
- CHEK2 (4)
- CNOT2 (4)
- COG6 (4)
- CPM (4)
- CPT1B (4)
- CR2 (4)
- ELL (4)
- ENPEP (4)
- ERG (4)
- FAF1 (4)
- FBXO6 (4)
- FBXW7 (4)
- FNDC8 (4)
- GARS (4)
- GATA3 (4)
- GSTT2 (4)
- H2AFY2 (4)
- HNRNPM (4)
- IL1RN (4)
- IQGAP1 (4)
- KRT8 (4)
- LIMK1 (4)
- MAD2L1BP (4)
- MAGEB4 (4)
- MLANA (4)
- MME (4)
- MRPS27 (4)
- MXD4 (4)
Antibody Hosts
Knockout (KO) Validation
Families
- Druggable Genome (992)
- Transmembrane (309)
- Transcription Factors (239)
- Protein Kinase (160)
- Secreted Protein (153)
- ES Cell Differentiation/IPS (120)
- Stem cell - Pluripotency (86)
- Protease (85)
- Adult stem cells (33)
- Embryonic stem cells (18)
- Nuclear Hormone Receptor (17)
- P450 (15)
- Induced pluripotent stem cells (13)
- Stem cell relevant signaling - JAK/STAT signaling pathway (11)
- Phosphatase (9)
- Cancer stem cells (8)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (8)
- Stem cell relevant signaling - DSL/Notch pathway (7)
- Stem cell relevant signaling - Wnt Signaling pathway (4)
- Ion Channels: Cys-loop Receptors (3)
- GPCR (2)
- Ion Channels: Other (2)
- Ion Channels: Potassium (2)
Pathways
- Metabolic pathways (193)
- Pathways in cancer (145)
- MAPK signaling pathway (100)
- Prostate cancer (100)
- Fc epsilon RI signaling pathway (88)
- Focal adhesion (88)
- Toll-like receptor signaling pathway (88)
- Colorectal cancer (86)
- Endometrial cancer (81)
- T cell receptor signaling pathway (81)
- ErbB signaling pathway (79)
- Neurotrophin signaling pathway (79)
- Fc gamma R-mediated phagocytosis (77)
- Non-small cell lung cancer (72)
- Pancreatic cancer (70)
- Progesterone-mediated oocyte maturation (70)
- Chronic myeloid leukemia (68)
- Melanoma (67)
- Acute myeloid leukemia (66)
- GnRH signaling pathway (66)
- Bladder cancer (65)
- Glioma (64)
- Regulation of actin cytoskeleton (63)
- B cell receptor signaling pathway (62)
- Renal cell carcinoma (60)
- Natural killer cell mediated cytotoxicity (59)
- Insulin signaling pathway (56)
- Thyroid cancer (55)
- Amyotrophic lateral sclerosis (ALS) (53)
- VEGF signaling pathway (53)
- Cell cycle (51)
- Chemokine signaling pathway (51)
- Melanogenesis (51)
- Wnt signaling pathway (45)
- Apoptosis (42)
- Small cell lung cancer (42)
- Cell adhesion molecules (CAMs) (40)
- Endocytosis (40)
- Gap junction (40)
- Hematopoietic cell lineage (40)
- Leukocyte transendothelial migration (40)
- Oocyte meiosis (39)
- Prion diseases (38)
- Vascular smooth muscle contraction (38)
- p53 signaling pathway (38)
- Jak-STAT signaling pathway (37)
- Type II diabetes mellitus (35)
- Dorso-ventral axis formation (34)
- Long-term depression (33)
- Cytokine-cytokine receptor interaction (32)
- Long-term potentiation (31)
- Purine metabolism (31)
- Adherens junction (29)
- Alzheimer's disease (28)
- Primary immunodeficiency (28)
- Basal cell carcinoma (24)
- Phosphatidylinositol signaling system (24)
- mTOR signaling pathway (24)
- Pyrimidine metabolism (23)
- Ubiquitin mediated proteolysis (23)
- Arachidonic acid metabolism (22)
- Valine (22)
- leucine and isoleucine degradation (22)
- Epithelial cell signaling in Helicobacter pylori infection (21)
- Fatty acid metabolism (21)
- Tight junction (21)
- Arginine and proline metabolism (19)
- Calcium signaling pathway (19)
- Huntington's disease (19)
- Pathogenic Escherichia coli infection (19)
- Adipocytokine signaling pathway (18)
- Axon guidance (17)
- Drug metabolism - cytochrome P450 (17)
- Metabolism of xenobiotics by cytochrome P450 (17)
- Retinol metabolism (17)
- Spliceosome (17)
- Complement and coagulation cascades (16)
- Glycerolipid metabolism (16)
- RNA degradation (16)
- Systemic lupus erythematosus (16)
- Lysosome (15)
- RIG-I-like receptor signaling pathway (15)
- TGF-beta signaling pathway (15)
- DNA replication (14)
- Glutathione metabolism (14)
- Glycolysis / Gluconeogenesis (14)
- Propanoate metabolism (14)
- Tryptophan metabolism (14)
- Antigen processing and presentation (13)
- Autoimmune thyroid disease (13)
- Base excision repair (13)
- Linoleic acid metabolism (13)
- Lysine degradation (13)
- Mismatch repair (13)
- Fatty acid elongation in mitochondria (12)
- Nucleotide excision repair (12)
- Allograft rejection (11)
- Caffeine metabolism (11)
- Proteasome (11)
- Renin-angiotensin system (11)
- Aminoacyl-tRNA biosynthesis (10)
- Butanoate metabolism (10)
- Histidine metabolism (10)
- Inositol phosphate metabolism (10)
- One carbon pool by folate (10)
- Parkinson's disease (10)
- Pyruvate metabolism (10)
- NOD-like receptor signaling pathway (9)
- Neuroactive ligand-receptor interaction (9)
- Oxidative phosphorylation (9)
- PPAR signaling pathway (9)
- Type I diabetes mellitus (9)
- ABC transporters (8)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (8)
- Fatty acid biosynthesis (8)
- Hedgehog signaling pathway (8)
- Viral myocarditis (8)
- beta-Alanine metabolism (8)
- Alanine (7)
- Asthma (7)
- Graft-versus-host disease (7)
- Notch signaling pathway (7)
- Starch and sucrose metabolism (7)
- Tyrosine metabolism (7)
- aspartate and glutamate metabolism (7)
- Amino sugar and nucleotide sugar metabolism (6)
- Cytosolic DNA-sensing pathway (6)
- Dilated cardiomyopathy (6)
- Drug metabolism - other enzymes (6)
- Glycerophospholipid metabolism (6)
- Nicotinate and nicotinamide metabolism (6)
- Terpenoid backbone biosynthesis (6)
- Vibrio cholerae infection (6)
- ECM-receptor interaction (5)
- Nitrogen metabolism (5)
- Pentose phosphate pathway (5)
- Synthesis and degradation of ketone bodies (5)
- Cardiac muscle contraction (4)
- Cysteine and methionine metabolism (4)
- Hypertrophic cardiomyopathy (HCM) (4)
- Ribosome (4)
- Sulfur metabolism (4)
- Selenoamino acid metabolism (3)
- Androgen and estrogen metabolism (2)
- Citrate cycle (TCA cycle) (2)
- Folate biosynthesis (2)
- Homologous recombination (2)
- Maturity onset diabetes of the young (2)
- Porphyrin and chlorophyll metabolism (2)
- Protein export (2)
- Regulation of autophagy (2)
- Taste transduction (2)
- Taurine and hypotaurine metabolism (2)
- Thiamine metabolism (2)
- Ascorbate and aldarate metabolism (1)
- Fructose and mannose metabolism (1)
- Glycine (1)
- Glyoxylate and dicarboxylate metabolism (1)
- Limonene and pinene degradation (1)
- Non-homologous end-joining (1)
- SNARE interactions in vesicular transport (1)
- Steroid biosynthesis (1)
- Vitamin B6 metabolism (1)
- serine and threonine metabolism (1)