PD-L1

PD-L1 and PD-L2 ligands function as key check-point regulators of the immune system. Immunotherapy with PD-1 and PD-L1 blocking monoclonal antibodies have improved the anti-tumor activities of patients? T-cells.

PD-L1 UltraMab™ Antibody

SKU#	TA591004
Clone Name	OR-5E3
Target	Homo sapiens CD274 molecule (CD274), transcript variant 1
Host	Rabbit
Reactivity	Human
Tested Application	IHC, ELISA
Dilution	IHC: 1:50-1:200

IHC staining of FFPE mouse spleen tissue with OR-5E3 shows positive staining of APC immune cells.

IHC staining of FFPE human Bladder cancer and Melanoma tissue with OR-5E3 and SP142 clone. OR-5E3 gives similar or stronger staining when compared to the FDA approved SP142 clone.

Antibodies against commonly studied proteins in cancer immunotherapy

Protein Name	Antibody Description	SKU
ARG1	ARG1 mouse monoclonal antibody, clone OTI4E6	TA502413
B7-1/CD80	CD80 mouse monoclonal antibody, clone UMAB65	UM500055
B7-H3/CD276	Rabbit Polyclonal CD276 Antibody	TA355034
B7-H4/VTCN1	Anti-VTCN1 mouse monoclonal antibody	TA810072
CD160	Rabbit Polyclonal Anti-CD160 Antibody	TA349762
CD19	CD19 mouse monoclonal antibody, clone UMAB103	UM500071
CD244	Rabbit Polyclonal Anti-CD244 Antibody	TA349773
IDO1	IDO1 mouse monoclonal antibody, clone UMAB126	UM500091
IL-10RA	IL10RA mouse monoclonal antibody, clone OTI1D10	TA506929
IL-13	IL13 mouse monoclonal antibody, clone OTI6D3	TA804004
IL-4	Rabbit polyclonal IL4 Antibody (C-term)	TA324803
LAG3	LAG3 mouse monoclonal antibody, clone OTI8F6	TA807082
MICA	Rabbit Polyclonal MICA Antibody	TA306443
MICB	anti MIC-B monoclonal antibody, cloneB-D55	AM31286AF-N
N-Cadherin	NCAM1/CD56 mouse monoclonal antibody, clone UMAB194	UM800086
Notch1	Anti-Notch1 mouse monoclonal antibody, clone OTI3E12	TA500078
PD-L1	PD-L1/CD274 mouse monoclonal antibody, clone OTI13G7	TA809809
PD-L2	PDL2/PDCD1LG2 mouse monoclonal antibody, clone OTI5A7	TA808997
SOX2	Rabbit Polyclonal Antibody against SOX2 - Embryonic Stem Cell Marker	TA301462
TIM3	HAVCR2 mouse monoclonal antibody, clone OTI2E2	TA807034
Beta Tubulin	Rabbit polyclonal anti-TUBB(beta Tubulin) antibody, Loading control	TA301569
Vimentin	Vimentin (VIM) mouse monoclonal antibody, clone UMAB160	UM800055