ORF Clones Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
MCM3AP MCM3AP and POMP Mutations Cause a DNA-Repair and DNA-Damage-Signaling Defect in an Immunodeficient Child Hum. Mutat., 2015 Nov ORF Clones RC218026
MCM7 Homozygous mutation in MCM7 causes autosomal recessive primary microcephaly and intellectual disability Journal of medical genetics, 2021 May ORF Clones RC213809
MCM7 Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion Oncogene (26 July 2010) doi:10.1038/onc.2010.287 Original Article, 2010 Jul ORF Clones RC203630
MCOLN2 TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway Nat Commun, 2019 Dec ORF Clones RC211195
MCOLN2 HIF-1a Inhibition Sensitized Pituitary Adenoma Cells to Temozolomide by Regulating Presenilin 1 Expression and Autophagy Technol. Cancer Res. Treat., 2016 Dec ORF Clones RG211195
MCU Distinct Properties of Ca2+ Efflux from Brain, Heart and Liver Mitochondria: The Effects of Na+, Li+ and the Mitochondrial Na+/Ca2+ Exchange Inhibitor CGP37157 Cell Calcium, 2021 Feb ORF Clones MR218926
MD2 PFKFB4 promotes lung adenocarcinoma progression via phosphorylating and activating transcriptional coactivator SRC-2 BMC pulmonary medicine, 2021 Feb ORF Clones RC204686
MD2 Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity bioRxiv, 2020 Jun ORF Clones RC204686
MDA5 Anti-MDA5 Antibody Spectrum in Western World Curr Rheumatol Rep, 2018 Oct ORF Clones RC215661
MDA5 A GTPase-activating protein binding protein (G3BP1) / antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells J. Biol. Chem., 2018 Apr ORF Clones RC215661
MDH2 Role of MDH2 pathogenic variant in pheochromocytoma and paraganglioma patients Genet. Med., 2018 Jul ORF Clones RC201095
MDM2 The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell-mediated antitumor immunity Nature immunology, 2021 Mar ORF Clones RC219518
MDM2 A feedforward circuit shaped by ECT2 and USP7 contributes to breast carcinogenesis Theranostics, 2020 Aug ORF Clones RC219518
MDM2 Estrogen receptor α promotes Cav1.2 ubiquitination and degradation in neuronal cells and in APP/PS1 mice Aging Cell, 2019 Apr ORF Clones MR207827
MDM2 Genetic evolution in chronic lymphocytic leukaemia Best Pract Res Clin Haematol, 2016 Mar ORF Clones RG219518
MDM2 Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations Blood, 2015 Dec ORF Clones RG219518
MDM4 Genetic evolution in chronic lymphocytic leukaemia Best Pract Res Clin Haematol, 2016 Mar ORF Clones RG209620
MDM4 Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations Blood, 2015 Dec ORF Clones RG209620
MDMX Phospho-?Np63?/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposure Cell Cycle, 2011 Nov ORF Clones RC209620
Mdp1 Glycolytic flux control by drugging phosphoglycolate phosphatase Nature Communications, 2022 Nov ORF Clones MR201315
MECP2 Fat-Specific Knockout of Mecp2 Upregulates Slpi to Reduce Obesity by Enhancing Browning Diabetes, 2020 Jan ORF Clones MR226839
MED1 Mediator subunit MED1 modulates intranuclear dynamics of the thyroid hormone receptor J. Cell. Biochem., 2019 Nov ORF Clones RG222118
MED12 Introduction of Somatic Mutation in MED12 Induces Wnt4/β-Catenin and Disrupts Autophagy in Human Uterine Myometrial Cell Reproductive Sciences, 2020 Jan ORF Clones RC217206
MED12 MED12 is recurrently mutated in Middle Eastern colorectal cancer Gut, 2017 Feb ORF Clones RC217206
Med13 Conversion of antigen-specific effector/memory T cells into Foxp3-expressing T reg cells by inhibition of CDK8/19. Science immunology, 2020 Jul ORF Clones MR224038
MED25 The Mediator complex subunit MED25 is targeted by the N-terminal transactivation domain of the PEA3 group members Nucleic Acids Res., May 2013; 41: 4847 - 4859., 2013 May ORF Clones RG209044
MED28 MED28 and forkhead box M1 (FOXM1) mediate matrix metalloproteinase 2 (MMP2)-dependent cellular migration in human nonsmall cell lung cancer (NSCLC) cells J. Cell. Physiol., 2018 Nov ORF Clones RC204304
MED28 MED28 Regulates Epithelial-Mesenchymal Transition Through NF?B in Human Breast Cancer Cells J. Cell. Physiol., 2016 Sep ORF Clones RC204304
MEF2C Induced cardiomyocyte maturation: Cardiac transcription factors are necessary but not sufficient PLoS ONE, 2019 Oct ORF Clones MR207045
MEF2C RNA-binding protein AUF1 promotes myogenesis by regulating MEF2C expression levels Mol. Cell. Biol., 2014 Jun ORF Clones RC220584
MEF2D Mef2d sustains activation of effector Foxp3+ Tregs during transplant survival and anticancer immunity J. Clin. Invest., 2020 Aug ORF Clones RC208748
MEF2D Dual-specificity tyrosine-phosphorylation regulated kinase 1A Gene Transcription is regulated by Myocyte Enhancer Factor 2D Sci Rep, 2017 Aug ORF Clones RC208748
MEF2D Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia EBioMedicine ORF Clones RC208748
MEGF10 MEGF10 functions as a receptor for the uptake of amyloid-β. FEBS letters, 2010 Oct ORF Clones RG217883
MEIS2 Transcriptomic and anatomic parcellation of 5-HT3AR expressing cortical interneuron subtypes revealed by single-cell RNA sequencing Nat Commun, 2017 Jan ORF Clones MG226569
MEK1 MAP2K1 and MAP3K1 mutations in langerhans cell histiocytosis Genes Chromosomes Cancer June 2015, 2015 Jun ORF Clones RC218460
MEK1 Identification of the MEK1(F129L) Activating Mutation as a Potential Mechanism of Acquired Resistance to MEK Inhibition in Human Cancers Carrying the B-RafV600E Mutation Cancer Res., Aug 2011; 71: 5535 - 5545., 2011 Aug ORF Clones RC218460
MEK2 Interaction of tRNA with MEK2 in pancreatic cancer cells Sci Rep, 2016 Jun ORF Clones RC201827
MEK4 Truncation- and motif-based pan-cancer analysis reveals tumor-suppressing kinases Sci Signal, 2018 Apr ORF Clones RC206051
MEK4 Truncation and Motif Based Pan-Cancer Analysis Highlights Novel Tumor Suppressing Kinases bioRxiv, 2018 Jan ORF Clones RC206051
MEK4 Registered report: Diverse somatic mutation patterns and pathway alterations in human cancers eLife, 2016 Feb ORF Clones RC206051
MEK4 Diverse somatic mutation patterns and pathway alterations in human cancers Nature (28 July 2010) doi:10.1038/nature09208 Letter, 2010 Jul ORF Clones RC206051
MEK7 Truncation- and motif-based pan-cancer analysis reveals tumor-suppressing kinases Sci Signal, 2018 Apr ORF Clones RC213868
MEK7 Truncation and Motif Based Pan-Cancer Analysis Highlights Novel Tumor Suppressing Kinases bioRxiv, 2018 Jan ORF Clones RC213868
MEK7 A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors Nat. Chem. Biol. July 2014, 2014 Jul ORF Clones RC213868
MEKK2 miRNA-106a directly targeting RARB associates with the expression of Na(+)/I(-) symporter in thyroid cancer by regulating MAPK signaling pathway J. Exp. Clin. Cancer Res., 2016 Jun ORF Clones RC223988
MEKK3 Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling Nature, 2016 Apr ORF Clones RC210317
MELK MELK is an oncogenic kinase essential for metastasis, mitotic progression, and programmed death in lung carcinoma Signal transduction and targeted therapy, 2020 Dec ORF Clones RC204245
MELK Phillygenin, a MELK Inhibitor, Inhibits Cell Survival and Epithelial-Mesenchymal Transition in Pancreatic Cancer Cells Onco Targets Ther, 2020 Apr ORF Clones RC204245
MELK Discovery of a novel kinase hinge binder fragment by dynamic undocking RSC Med. Chem., 2020 Mar ORF Clones RC204245