SFTPB Mouse Monoclonal Antibody [Clone ID: 1B9]

CAT#: AM00341SU-N

SFTPB mouse monoclonal antibody, clone 1B9, Supernatant


USD 570.00

5 Days*

Size
    • 1 ml

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Specifications

Product Data
Clone Name 1B9
Applications IF, IHC
Recommended Dilution Immunofluorescence.
Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/100
Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended.
Use Polymer anti Mouse/Rabbit IgG as a detection system.
Positive Control: Lung adenocarcinoma.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant Surfactant Protein B.
Specificity This antibody detects Surfactant Protein B (Mature).
Cellular Localization: Cytoplasmic.
Formulation State: Supernatant
State: Liquid Tissue Culture Supernatant with 0.2% BSA and 15mM Sodium Azide.
Storage Store the antibody undiluted at 2-8°C.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens PMS1 homolog 2, mismatch repair system component (PMS2), transcript variant 1
Background ProSP-B is glycosylated in the Golgi apparatus and undergoes carboxy- and amino-terminal proteolysis by a cathepsin D-like protease. Pulmonary surfactant is a complex mixture of phospholipids and proteins that is secreted from type II cells in alveoli and reduces the surface tension at the alveolar air-liquid interface, providing alveolar stability necessary for normal ventillation. Four distinct proteins isolated from pulmonary surfactant are termed surfactant proteins A, B, C, and D. SP-A (28-36kDa) and SP-D (43kDa) are collagenous carbohydrate-binding proteins, whereas SP-B (8-9kDa) and SP-C (4kDa) are non-collagenous hydrophobic proteins. SP-B is expressed in pulmonary adenocarcinomas with acinar, papillary, bronchioloalveolar, and solid growth patterns. Squamous cell and large cell carcinomas of the lung and nonpulmonary adenocarcinomas do not express SP-B.
Synonyms Surfactant protein B, SP-B, SFTP3
Reference Data
Protein Families Druggable Genome
Protein Pathways Mismatch repair

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.